What remains to be thought

Is the pursuit of the truth an altruistic objective?— Rand

Does there exist meaning outside of what is constructed through experience—i.e., through man's interaction with reality?

Id est:

Does there exist any truth outside of what is relevant in reality?— constructivism

How is relevance established?

What is the role of verification in establishing relevance?— Ayer

What are the necessary rules/methodologies/procedures that must be followed to conclusively 'verify something?— Popper